產品介紹
Advantages of BIOTANIUM for dental implants
類別:BIOTANIUM
發佈日期範圍:100/11/30 ~
Advantages of BIOTANIUMTM (nanostructured titanium) for dental implants
Nanostructuring commercial purity titanium provides specific advantages for dental implants. The greatest advantage is the bioactive characteristic of nanostructured titanium surfaces. A growing body of university and clinical research since 2004 has consistently demonstrated that bone forming cells attach 40% to 134% more rapidly to the surface of nanostructured titanium (see figure below comparing conventional and nanostructured grade 4 titanium surfaces etched with hydrofluoric acid). Most recent studies have shown that the proliferation of preosteoblastic cells (MC3T3-E1) after 7 and 12 days is consistently more than 19 times greater on nanostructured grade 2 titanium compared to conventional titanium. This research supports the prospect of greatly reduced patient healing times. In addition, nanostructuring typically doubles the strength of the most accepted dental implant material, pure titanium, increasing the structural safety margins in all existing designs and allowing smaller, more compact implant designs. Implants less than 2 mm in diameter are readily fabricated, ideal for replacing the small teeth in the lower front jaw. Furthermore, since the elastic modulus of titanium is unchanged by the nanostructuring, the rigidity of a compact nanostructured titanium implant is effectively half that of a comparable conventional implant, matching more closely the structural properties of bone. This increases bone-implant compatibility and reduces factors that contribute to bone resorption.



The size scale of the structures imparted to the titanium by nanostructuring closely matches the structural scale of bone forming cells. Nanostructured titanium possesses an ultrafine scale crystalline surface topography and a density of grain boundaries that is at least 25,000 times greater than conventional titanium. This bioactive scaffolding for bone cell attachment is intrinsic to the material and does not require any special coatings to obtain. Furthermore, studies are underway now to determine how the extra energy contained in nanoscale grain boundaries produced via SPD enhance the formation of surface titanium oxides to make nanostructured titanium rapidly self-reconstructing. For the dental implant patient, the rapid attachment of bone cells translates to reduced post-surgery healing times, simplified surgical implantation procedures, and an unlimited ability for the implant to continuously rebuild the ultrafine surface oxides throughout the life of the implant.
Use of nanostructured titanium offers additional advantages for dental implant manufacturers. Multiple studies have documented the superior machinability of SPD-produced nanostructured titanium. Implants can be fabricated with lower cutting tool wear, higher feed rates, and greater cutting depth, all while attaining smoother surface finish. These enhancements are due to the additional nanoscale deformation mechanisms that operate only in nanosturctured metals, and do not occur in conventional metals. In addition, because of the ultra small grain size, nanostructured titanium parts can to be superplastically formed to precise tolerances without any machining. The aerospace and sports products industries already avail themselves of this cost saving fabrication technology. Only with the introduction of nanostructuring of metals and alloys like titanium that are used in medical devices can superplastic forming now be economically implemented in the medical device industry.